With this project we aim to provide a forum for professionals that are involved in the management of patients with Cardiac Amyloidosis (CA) at every stage of their career, where to find a training and awarding opportunity to increase their awareness and improve their practice on the use of nuclear scintigraphy with bone seeking radiopharmaceuticals in the diagnostic work-up along with other multimodality imaging techniques. The focus will lie on transthyretin amyloidosis cardiomyopathy (ATTR-CM). The main focus in this project is Europe as a whole where 99mTc-DPD and 99mTc-HMDP as these are the most widely use radiopharmaceuticals in Europe.
Objectives of the course:
course content
| Phase 1 (launched): | |
| Pre-Assessment | Multiple Choice Questions |
| Module 1 | Introduction to Cardiac Amyloidosis and New Treatment Options Hans Nienhuis (Groningen, Netherlands) |
| Introduction to Cardiac Amyloidosis and Novel Therapeutic Options Claudio Rapezzi (University of Ferrara – Ferrara, Italy) |
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| Echocardiography and Cardiac MRI in Cardiac Amyloidosis Olivier Lairez (Toulouse, France) |
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| How to use CMR in Cardiac Amyloidosis Marianna Fontana (University College London Hospitals – London, UK) |
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| Self-assessment | |
| Module 2 – Nuclear Medicine Imaging in Cardiac Amyloidosis | Imaging Cardiac Amyloidosis Sharmila Dorbala (Brigham and Women’s Hospital – Boston, USA) |
| Nuclear Medicine Application in Amyloidosis: Cardiac MIBG – Protocols, Interpretation, Quantification Eve Piekarski (Paris, France) |
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| Nuclear Medicine Application in Amyloidosis – New PET Radiopharmaceuticals in Cardiac Amyloidosis, Perspectives Jens Sörensen (Uppsala, Sweden) |
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| Cardiac Bone Scans – Protocols, Interpretation, Quantification: an Overview Riemer Slart (Groningen, Netherlands) |
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| Self-assessment | |
| Phase 2 (launched): | |
| Module 3 – Case examples of Modules 1 and 2 | Case 1 (by Riemer Slart) |
| Case 2 (by Riemer Slart) | |
| Case 3 (by Alessia Gimelli) | |
| Case 4 (by Hans Nienhuis) | |
| Case 5 (by Hans Nienhuis) | |
| Case 6 (by Hans Nienhuis) | |
| Case 7 (by Hans Nienhuis) | |
| Self-assessment | |
| Module 4 – Radio-pharmaceuticals for Cardiac Amyloidosis |
General overview: what is available? |
| Bone seeking radiopharmaceuticals: secret of localisation and biodistribution and practical aspects of preparation and quality controls | |
| Self-assessment | |
| Module 5 – Nuclear Medicine Imaging in Cardiac Amyloidosis |
Case 1 (by Alessia Gimelli) |
| Case 2 (by Riemer Slart) | |
| Case 3 (by Riemer Slart) | |
| Case 4 (by Riemer Slart) | |
| Case 5 (by Alessia Gimelli) | |
| Case 6 (by Alessia Gimelli) | |
| Self-assessment | |
| Module 6 – Imaging acquisition and reading |
Protocol for bone scintigraphy in cardiac amyloidosis (Riemer Slart) |
| Planar and SPECT, visual and semiquantitative and quantitative (Alessia Gimelli) | |
| SPECT Evaluation for ATTR Cardiac Amyloidosis (Alessia Gimelli) | |
| Results EU questionnaire on cardiac amyloidosis and cardiac sarcoidosis (Alessia Gimelli) | |
| Self-assessment | |
| Phase 3 (launched): | |
| Module 7 (1 CME credit) – Clinical Cases and Multimodality Imaging | Case 1 (by Riemer Slart and Hans Nienhuis) |
| Case 2 (by Riemer Slart and Hans Nienhuis) | |
| Case 3 (by Riemer Slart and Hans Nienhuis) | |
| Case 4 (by Riemer Slart and Hans Nienhuis) | |
| Indication to bone scan in Cardiac Amyloidosis and patient selection (by Riemer Slart) | |
| Self-assessment | |
| Module 8 (1 CME credit) |
How to integrate bone scan in the clinical workout (by Alessia Gimelli) |
| Case 1 (by Riemer Slart and Hans Nienhuis) | |
| Case 2 (by Riemer Slart and Hans Nienhuis) | |
| Self-assessment | |
| Final Assessment | Multiple Choice Questions |
| Phase 4 (launch tbc): | |
| Module 9 – Therapy | Therapy – discussing the principle of therapy in amyloidosis (by Laura Obici) |
| Patient Selection for treatment initiation with a special emphasis on the role of imaging (by Amelia Jimenez Heffernan) | |
| Treatment Regiment (by Hans Nienhuis) | |
| Monitoring Patients during Treatment (by Peter van der Meer) | |
| Self-assessment | |
| Module 10 – Monitoring Treatment |
The role of clinical parametres and biomarkers and the role of imaging in treatment monitoring (by Francesco Bandera) |
| When to use which treatment in which patient – Case discussion | |
| Self-assessment | |
| Phase 5 (launch tbc): | |
| Module 11 – Case discussions | Case presentations by speakers and EURO-LEARN participants |
| Self-assessment | |
| Phase 6 (launch tbc): | |
| Module 12 –Multidisciplinary Discussion | Multidisciplinary Discussions of Cases |
| Expert Discussions | |
| Self-assessment | |
The programme is subject to change.
course format and lenghts
This freely accessible course will take place online. The course is divided in the following phases:
NEW:
The release dates are subject to change.
Please note, that the given time frames indicate the opening time of each phase and how long CME accreditation will be possible.
Certification
Phase 1 (October 2021 – October 2023):
Module 1: This Module is accredited with 1 European CME credit (ECMEC), assigned by the EACCME.
Module 2: This Module is accredited with 1 European CME credit (ECMEC), assigned by the EACCME.
Phase 2 (March 2022 – March 2024):
Module 3: This Module is accredited with 1 European CME credit (ECMEC), assigned by the EACCME.
Module 4: This Module is accredited with 1 European CME credit (ECMEC), assigned by the EACCME.
Module 5: This Module is accredited with 1 European CME credit (ECMEC), assigned by the EACCME.
Module 6: This Module is accredited with 1 European CME credit (ECMEC), assigned by the EACCME.
Phase 3 (August 2022 – August 2024):
Module 7: This Module is accredited with 1 European CME credit (ECMEC), assigned by the EACCME.
Module 8: This Module is accredited with 1 European CME credit (ECMEC), assigned by the EACCME.
When a module has been completed in the above mentioned time frame, an accreditation certificate will be awarded.
eLearning platform and registration
The course will take place on the ESMIT eLearning platform: elearning.eanm.org
To sign up, please follow these steps:
EURO-LEARN is here to educate, create a knowledge base for patients and specialists to exchange knowledge and experiences. We want to provide support in two ways – both for patients and for doctors who can explore the disease, learn to recognise it in advance and increase international relationships between specialists to help and ensure the development of medical knowledge. This is made possible with the certified eLearning course on Cardiac Amyloidosis!
